[Editor’s Note: This guest post is contributed by Blaine Bettinger. Blaine is the author of The Genetic Genealogist, a blog that examines the intersection of genetics and ancestry, and a patent attorney at Bond, Schoeneck & King in Syracuse, NY.]
As you may have heard, I recently made my 23andMe and Family Tree DNA autosomal testing results available for download online at “mygenotype,” and dedicated the information to the public domain (if dedicating DNA sequence to the public domain is even possible – I’m currently doing some research in this area and expect to write more in the future). [Editor's Note: see additional comments on personal genomics data in the public domain at the end of this post.]
At “mygenotype” you can download the following:
My Family Tree DNA Results:
- Affymetrix Autosomal DNA Results (2010)
- Affymetrix X-Chromosome DNA Results (2010)
- Illumina Autosomal DNA Results (2011)
- Illumina X-Chromosome DNA Results (2011)
My 23andMe Results:
- V2 Results (2008)
- V3 Results (2010)
- Y-DNA Results (2010)
- mtDNA Results (2010)
You can also find my SNPedia Promethease reports:
- Promethease Report using an early version of Affymetrix Family Finder DNA Results
- Promethease Report using V2 23andMe DNA Results
- Promethease Report using pooled 23andMe and Family Finder DNA Results
A Challenge To YOU
Now that the information is out there, available to anyone who might be interested, it remains to be seen who might be interested in the information.
Indeed, as evidenced by Razib’s spreadsheet, while dedicating a genome to the public domain has only been done by a small handful of people worldwide, it isn’t as novel as it was just a few months ago.
So, I’m challenging everyone who reads this to download my data and analyze it to find the most interesting or surprising results. For example, you could use my most recent 23andMe V3 data.
I’ve already done a fair amount of analysis myself, including the Promethease reports above (and see here), and a recent blog post about my vastly increased Type 2 Diabetes risk. However, perhaps there’s a recent but relatively study that applies, or perhaps there’s a story you can weave with a handful of SNPs. Or, even better, what can you tell me about my ancestry other than mtDNA and Y-DNA haplogroups? Don’t worry about the strength of the study, reproducibility, etc. – I’m aware of the uncertainties associated with this type of research, and my goal here is to make people aware of possibilities.
Please post your findings in the comments below, and in two weeks I’ll pick the most surprising or interesting findings and make them the focus of a new blog post.
Can you surprise me with my own genome?
[Editor’s Note: the data from Genomes Unzipped members, as well as data from other public genomics projects, including the Personal Genome Project, has been made available using the Creative Commons copyright and database rights waiver, CC0. (See previous GNZ coverage.) However, as this FAQ points out, CC0 is not necessarily a complete or universal waiver of all rights in the subject matter, including personal genomic data. As the publication of personal genomic data becomes more commonplace, and particularly as lawmakers seek to alter individuals’ rights in genomic data on the fly, it is probably only a matter of time before these tools are tested in practice.]