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Questioning the Evidence for Non-Canonical RNA Editing in Humans

In May 2019, it was reported in an article that over ten thousand sequence mismatches were observed between messenger RNA and DNA from the same individuals. More recently, three technical comments were published by Science surrounding this article. It was concluded that at least 90% of the Li et al. RDD sites are technical artifacts. …

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Notes on the Evidence for Extensive RNA Editing in Humans

The common notion running through molecular biology is that the information present in DNA is transferred to RNA and then to protein.  Back in 2010, researchers made a potentially ground-breaking observation.  They found that within any given individual, there are tens of thousands of places where transcribed RNA does not match the template DNA from …

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