At the risk of turning Friday Links into a self-trumpet-blowing occasion, we are happy to report that a number of GNZ contributors (Jeff, Carl and Luke) are authors on a new Crohn’s disease GWAS meta-analysis of 6000 patients that came out in Nature Genetics this week. The study brings the number of Crohn’s associations up to 71, with 30 novel, bringing the proportion of heritability explained up to about 24%; also worth noting that all of the associations from the previous meta-analysis were replicated it this one, showing how the cross-platform independent replication experiments that are now standard have largely obliterated false positives in GWAS. There were also 5 loci that showed evidence of a second, independent signal, which I think is a promising sign of things to come.
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Authors Elsewhere
- Daniel MacArthur: Gene Therapy Emerges From Disgrace to Be the Next Big Thing, Again
- Luke Jostins: ASHG2012: Who does family studies?
- Luke Jostins: Some updates
- Jan Aerts: Available: Research position Biological Data Visualization and Visual Analytics
- Jan Aerts: Postdoc position available: visualization and genomic structural variation discovery
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