I thought I’d point out a review article in Human Molecular Genetics that just came out in (open access) preprint form by Luke and myself on genetic risk prediction in complex disease. In it we discuss some of the strengths and weaknesses of genetic and risk prediction compared to classical epidemiological predictors, different statistical modelling considerations, and the effect of GWAS on prediction. Readers of this space might find the conclusion of some interest, where we consider some of the societal aspects of trying to bring the interpretation of genomes into mainstream medical practice.
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Authors Elsewhere
- Daniel MacArthur: Gene Therapy Emerges From Disgrace to Be the Next Big Thing, Again
- Luke Jostins: ASHG2012: Who does family studies?
- Luke Jostins: Some updates
- Jan Aerts: Available: Research position Biological Data Visualization and Visual Analytics
- Jan Aerts: Postdoc position available: visualization and genomic structural variation discovery
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